Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic
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چکیده
منابع مشابه
Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic.
The sperm chromatin structure assay (SCSA) was used to measure over 500 human semen samples from two independent studies: Study I, 402 samples from 165 presumably fertile couples wishing to achieve pregnancy over 12 menstrual cycles; Study II, samples from 115 patients seeking fertility counselling. The SCSA measures susceptibility to DNA denaturation in situ in spermatozoa exposed to acid for ...
متن کاملThe sperm chromatin structure assay as a diagnostic tool in the human fertility clinic.
BACKGROUND Sperm DNA integrity has been shown to be necessary for achieving and sustaining embryo development. The objective was to evaluate the sperm chromatin structure assay (SCSA) as a diagnostic tool in clinical practice for intrauterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatments. METHODS A total of 385 semen samples from 234 c...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 1460-2350
DOI: 10.1093/humrep/14.4.1039